Research

Functional lipid droplets as aAPCs

[9] S. Michelis, C. Pompili, B. Dumat, F. Niedergang, J. Fattaccioli, J.-M. Mallet. FRET-sensing of receptor binding at the interface of targeted biomimetic microparticles functionalized with tunable fluorescent lipids
ChemRxiv (2024) DOI : 10.26434/chemrxiv-2023-7cfwq
In Press

[8] J. Pineau, L. Pinon, J. Fattaccioli* , P. Pierobon* (2023). Functionalized Lipid Droplets and Microfluidics Approach to Study Immune Cell Polarity In Vitro. In: Baldari, C.T., Dustin, M.L. (eds) The Immune Synapse. Methods in Molecular Biology, vol 2654. Humana, New York, NY. DOI

[7] L. Pinon , N. Ruyssen , J. Pineau , O. Mesdjian , D. Cuvelier , R. Allena , S. Asnacios , A. Asnacios , P. Pierobon* , and J. Fattaccioli*. Phenotyping Polarization Dynamics Of Immune Cells Using A Lipid Droplet – Cell Pairing Microfluidic Platform.
Cell Reports Methods (2022) DOI (In press).

[6] J. Pineau, L. Pinon, O. Mesdjian, J. Fattaccioli, A.-M. Lennon-Duménil, P. Pierobon* . Microtubules restrict F-actin polymerization to the immune synapse via GEF-H1 to maintain polarity in lymphocytes.
eLife (2022) [DOI]

[5] B. Dumat‡, L. Montel‡, P. Matton, L. Pinon, L. Cattiaux, J. Fattaccioli*, J.M. Mallet*. Mannose-coated fluorescent emulsion droplets: specific biosensors for Mannose Receptor-induced phagocytosis.
ACS Applied Bio Materials., 2, 11, 5118-5126 (2019) [doi]
‡: equal contribution to the work

[4] L. Montel, L. Pinon,  J. Fattaccioli*. 
A multiparametric, quantitative and high-throughput assay to determine the influence of target size on phagocytic uptake.
Biophys. J., 117 (3) pp. 408-419 (2019) [doi]
Preprint available on BioRxiv (2019) [Link to BioRXiv]

[3] L. Pinon, L. Montel, O. Mesdjian, M. Bernard, A. Michel, C. Ménager, J. Fattaccioli*. Kinetically-enhanced fabrication of homogeneous biomimetic and functional emulsion droplets.
Langmuir, 34 (50), pp 15319–15326  (2018) [doi][url]

[2] D. Molino, S. Quignard, C. Gruget, F. Pincet, Y. Chen, M. Piel, J. Fattaccioli*.
On-chip quantitative measurement of mechanical stresses during cell migration with emulsion droplets.
Scientific Reports 6, 29113 (2016)[pdf][doi].

[1] K. Ben M’Barek, D. Molino, S. Quignard, Y. Chen, P. Chavrier and J. Fattaccioli*
Phagocytosis of Immunoglobulin-Coated Emulsion Droplets
Biomaterials 51, 270-277  (2015). [pdf][doi]

Microfluidic trapping arrays

[6] N. Ruyssen*, G. Fina, R. Allena, M.C. Jullien, J. Fattaccioli.
Spanwise dispersion optimizes the efficiency of dense microfluidic trap arrays
Arxiv (2024) Link
Under review

[5] L. Pinon , N. Ruyssen , J. Pineau , O. Mesdjian , D. Cuvelier , R. Allena , S. Asnacios , A. Asnacios , P. Pierobon* , and J. Fattaccioli*. Phenotyping Polarization Dynamics Of Immune Cells Using A Lipid Droplet – Cell Pairing Microfluidic Platform.
Cell Reports Methods (2022) DOI (In press).

[4] O. Mesdjian‡, N. Ruyssen‡, M.-C. Jullien, R. Allena, J. Fattaccioli*. Enhancing the capture efficiency and homogeneity of single-layer flow-through trapping microfluidic devices using oblique hydrodynamic streams.
Microfluidics and Nanofluidics, 25, 91 (2021) [doi]
Post-review preprint avaiable on the ArXiv (2021) [url]

[3] K. Sakai, F. Charlot, T. Le Saux, S. Bonhomme, F. Nogué, J.C. Palauqui*, J. Fattaccioli*. 
Design of a microfluidic and microscopic toolbox for the ultra-wide spatio-temporal study of plant protoplast development and physiology.
Plant Methods, 15, n° 19 (2019) [doi]
Preprint available on BioRxiv [Link to BioRXiv]
Highlighted in the french magazine La Recherche (Nov. 2019) [url][pdf]

Bacterial biofilms

[2] M. Prasad, N. Obana, S.-Z. Lin, K. Sakai, C. Blanch-Mercader, J. Prost, N. Nomura, J.-F. Rupprecht*, J. Fattaccioli*, A. S. Utada*
Alcanivorax borkumensis Biofilms Enhance Oil Degradation By Interfacial Tubulation
Science (Accepted), 2023
BioRxiv (2022) 2022.08.06.503017; doi: https://doi.org/10.1101/2022.08.06.503017

[1] M. Prasad, N. Obana, K. Sakai, Y. Nakayama, S. Miyazaki, M. Toyofuku, J. Fattaccioli, N. Nomura, A.S. Utada*
Point mutations lead to increased levels of c-di-GMP and phenotypic changes to colony biofilm morphology in Alcanivorax borkumensis SK2.
Microbes and Environnements. 34 (1) pp. 104-107 (2019) [doi][pdf]

Sophisticated microparticles

[5] L. Pinon, L. Montel, O. Mesdjian, M. Bernard, A. Michel, C. Ménager, J. Fattaccioli*. Kinetically-enhanced fabrication of homogeneous biomimetic and functional emulsion droplets.
Langmuir, 34 (50), pp 15319–15326  (2018) [doi][url]

[4] S. Quignard*, G. Frébourg, Y. Chen, J. Fattaccioli.
*Nanometric emulsions encapsulating solid particles as alternative carriers for intracellular delivery.
Nanomedicine, 11 (16), 2059-2072 (2016) [pdf].

[3] O. Mesdjian, Y. Chen, J. Fattaccioli*
Luminescent and Absorptive Metal-Coated Emulsions for Micro-Velocimetry
Microelectronic Engineering 158, 69-74 (2016). [pdf][doi].

[2] S. Quignard, Y. Chen, M. d’Ischia and J. Fattaccioli*
UV-induced fluorescence of polydopamine-coated emulsion droplets.
ChemPlusChem 79 (9),  1254-1257 (2014). [pdf][doi]
Article highlighted in Wiley-VCH Hot Topics – Surfaces and Interfaces. [link]

[1] G.M. Nocera, K. Ben M’Barek, D.G. Bazzoli, G. Fraux, M. Bontems-Van Heijenoort, J. Chokki, S. Georgeault, Y. Chen, and J. Fattaccioli*
Fluorescent microparticles fabrication through chemical coating of O/W emulsion droplets with a thin metallic film.
RSC Advances 4 (23), 11564 – 11568 (2014). [pdf][doi]